All Rights Reserved Copyright © 2011-2014 Ultracet
Cases of acute pancreatitis have been reported rarely with acetaminophen ultracet information use.
One study has suggested that acetaminophen may precipitate acute biliary pain and cholestasis.
The mechanism of this effect may be related to inhibition of prostaglandin and alterations in the
regulation of the sphincter of Oddi. Psychiatric Psychiatric side effects including somnolence,
anorexia, insomnia, anxiety, confusion, euphoria, amnesia, depersonalization, depression, drug abuse,
emotional lability, hallucination, impotence, paroniria morbid dreaming, abnormal thinking, and nervousness
have been reported. Suicidal tendency has been reported with the use of tramadol but a
causal ultracet information association has not been determined.
Dermatologic side effects including increased sweating, pruritus, and rash have been reported.
Nervous system Nervous system side effects including dizziness, headache, tremor, ataxia, convulsions,
hypertonia, migraine, aggravated migraine, ultracet information involuntary muscle contractions, paraesthesia,
stupor, and vertigo have been reported. Cognitive dysfunction and difficulty concentrating have been reported
with the use of tramadol ultracet information but a causal association has not been determined.
Genitourinary side effects including prostatic disorder, albuminuria, micturition disorder, oliguria, and
urinary retention have been reported. General General side effects including asthenia, fatigue, hot flushes,
chest pain, rigors, syncope, and withdrawal syndrome have been reported.
Cardiovascular side effects including hypertension, aggravated hypertension, arrhythmia, palpitation,
tachycardia, and hypotension have been reported. Vasodilation, orthostatic hypotension, and myocardial ischemia
have been reported with the use of tramadol but a causal association has not been determined.
Other side effects including tinnitus and weight decrease have been reported. Serotonin syndrome has been
reported with the use of tramadol when taken concomitantly with other serotonergic agents such as SSRIs and MAOIs.
Hepatic Alcoholic patients may develop hepatotoxicity after even modest doses of acetaminophen. In healthy patients,
approximately grams of acetaminophen is necessary to deplete liver glutathione stores by in a kg person.
However, hepatotoxicity has been reported following smaller doses. Glutathione concentrations may be repleted by the antidote Nacetylcysteine.
One case report has suggested that hypothermia may also be beneficial in decreasing liver damage during overdose.
In a recent retrospective study of patients admitted for acetaminophen overdose.
A ultracet information yearold female developed hepatotoxicity, reactive plasmacytosis and agranulocytosis
followed by a leukemoid reaction after acute acetaminophen toxicity. Hepatic side effects including abnormal hepatic
function have been reported. Hepatitis, liver failure, and elevated liver function test have been reported with the use
of tramadol but a causal association has not been determined. Hepatic side effects of acetaminophen including
severe and sometimes fatal dose dependent hepatitis have been reported in alcoholic patients.
Several cases of hepatotoxicity from chronic acetaminophen therapy at therapeutic doses have also been
reported despite a lack of risk factors for toxicity. Hematologic Hematologic side effects including anemia have been reported.
Hematologic side effects including rare cases of thrombocytopenia associated with acetaminophen have been reported. Acute thrombocytopenia has also been reported as having been caused by sensitivity to acetaminophen glucuronide, the major metabolite of
acetaminophen. Methemoglobinemia with resulting cyanosis has been observed in the setting of acute overdose. Respiratory Respiratory side effects including dyspnea have been reported. Pulmonary edema has been reported with the use of tramadol but a causal association has not been determined. Ocular Ocular side effects including abnormal vision have been reported. Hypersensitivity Hypersensitivity side effects including anaphylaxis, ultracet information urticaria, StevensJohnson syndromeTENS have been reported with the use of tramadol but a causal
association has not been determined. Allergic reaction including primarily skin rash and hypersensitivity secondary to acetaminophen have rarely been reported. Allergic ultracet information reactions and hypersensitivity secondary to acetaminophen have generally been controlled by discontinuation of the drug and, if necessary, symptomatic treatment. Renal Renal side effects including elevated creatinine has been reported with the use of tramadol but a causal association has not been determined. Metabolic Metabolic side effects including metabolic acidosis have been reported following a massive overdose of acetaminophen. In the case of metabolic acidosis, causality is uncertain as more than one drug
was ingested. The case of metabolic acidosis followed the ingestion of grams of acetaminophen,. grams of aspirin, and a small amount of a liquid household cleaner. The patient also had a history of seizures which the authors reported may have contributed to an increased lactate level indicative of metabolic acidosis. Pronunciation Generic Name acetaminophen and tramadol a SEET a MIN o fen and TRAM a dol Brand Names Ultracet contains a combination of tramadol and acetaminophen. Acetaminophen is a less potent pain reliever that increases the
effects of tramadol. Ultracet may also be used for purposes not listed in this medication guide. Important information about Ultracet You should not take Ultracet if you are allergic to acetaminophen or tramadol, if you are intoxicated drunk, or if you have recently used narcotic pain medicine, a sedative or tranquilizer, medicine for depression or mental illness, or any type of street drug. Do not drink alcohol while you are taking Ultracet. Alcohol may cause a dangerous decrease in your breathing when used together with Ultracet. Alcohol may also increase your
risk of liver damage while taking acetaminophen. Tell your doctor if you have ever had alcoholic liver disease cirrhosis or if you drink more than alcoholic beverages per day. You may not ultracet information be able to take medicine that contains acetaminophen. Do not take more of this medication than is recommended. An overdose can damage your liver or cause death. The maximum amount of is ultracet information tablets per dose, or tablets per day. Ultracet may be habitforming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a ultracet information
place where others cannot get to it. Before taking Ultracet You should ultracet information not take if you are allergic to acetaminophen or tramadol, if you are intoxicated drunk, or if you have recently used any of the following drugs alcohol tramadol Ultram or narcotic pain medicine ultracet information sedatives or tranquilizers such as Valium medicine for depression or anxiety medicine for mental illness such as bipolar disorder, schizophrenia or street drugs. Tell your doctor if you have ever had alcoholic liver disease cirrhosis or if you drink more than alcoholic
beverages per day. You may not be able to take medicine such as Ultracet, that contains acetaminophen. Seizures have occurred in some people taking. Your risk of a seizure may be higher if you have any ultracet information of these conditions a history of drug or alcohol addiction
a ultracet information history of epilepsy or other seizure disorder a history of head injury a metabolic disorder an infection of your brain or spinal cord, such as meningitis or encephalitis if you are also taking an antidepressant, mood stabilizer, or another narcotic pain medicine or if you have taken an MAO inhibitor such as isocarboxazid Marplan, linezolid Zyvox, phenelzine Nardil, rasagiline Azilect, selegiline Eldepryl, Emsam, or tranylcypromine Parnate within the past days.